| Début |
Fin |
Symbole |
Description |
| 1807 |
2169 |
PAU8 |
hypothetical
protein |
|
| 2480 |
2707 |
YAL067W-A |
Putative
protein of unknown function; identified by gene-trapping,
microarray-based expression analysis, and genome-wide homology searching |
|
| 7236 |
9017 |
SEO1 |
Putative
permease, member of the allantoate transporter subfamily of the major
facilitator superfamily; mutation confers resistance to ethionine
sulfoxide |
|
| 11566 |
11952 |
YAL065C |
Putative
protein of unknown function; has homology to FLO1; possible pseudogene |
|
| 12047 |
12427 |
YAL064W-B |
Fungal-specific
protein of unknown function |
|
| 13364 |
13744 |
YAL064C-A |
Putative
protein of unknown function; YAL064C-A is not an essential gene |
|
| 21526 |
21852 |
YAL064W |
Protein of
unknown function; may interact with ribosomes, based on co-purification
experiments |
|
| 22397 |
22687 |
YAL063C-A |
Putative
protein of unknown function; identified by expression profiling and
mass spectrometry |
|
| 24001 |
27969 |
FLO9 |
Lectin-like
protein with similarity to Flo1p, thought to be expressed and involved
in flocculation |
|
| 31568 |
32941 |
GDH3 |
NADP(+)-dependent
glutamate dehydrogenase, synthesizes glutamate from ammonia and
alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs
from Gdh1p; expression regulated by nitrogen and carbon sources |
|
| 33449 |
34702 |
BDH2 |
Putative
medium-chain alcohol dehydrogenase with similarity to BDH1;
transcription induced by constitutively active PDR1 and PDR3; BDH2 is
an essential gene |
|
| 35156 |
36304 |
BDH1 |
NAD-dependent
(2R,3R)-2,3-butanediol dehydrogenase, a zinc-containing medium-chain
alcohol dehydrogenase, produces 2,3-butanediol from acetoin during
fermentation and allows using 2,3-butanediol as a carbon source during
aerobic growth |
|
| 36510 |
37148 |
ECM1 |
Protein
of unknown function, localized in the nucleoplasm and the nucleolus,
genetically interacts with MTR2 in 60S ribosomal protein subunit export |
|
| 37465 |
38973 |
CNE1 |
Calnexin;
integral membrane ER chaperone involved in folding and quality control
of glycoproteins; chaperone activity is inhibited by Mpd1p, with which
Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not
yet shown in yeast |
|
| 39260 |
41902 |
GPB2 |
Proposed
beta subunit of the heterotrimeric G protein; interacts with the
receptor Grp1p, affects signaling by altering the level of
phosphorylation of PKS substrates; regulates pseudohyphal growth
through cAMP levels; homolog of Gpb1p |
|
| 42178 |
42720 |
PEX22 |
Putative
peroxisomal membrane protein required for import of peroxisomal
proteins, functionally complements a Pichia pastoris pex22 mutation |
|
| 42882 |
45023 |
ACS1 |
Acetyl-coA
synthetase isoform which, along with Acs2p, is the nuclear source of
acetyl-coA for histone acetlyation; expressed during growth on
nonfermentable carbon sources and under aerobic conditions |
|
| 45900 |
48251 |
FLC2 |
Putative FAD
transporter; required for uptake of FAD into endoplasmic reticulum;
involved in cell wall maintenance |
|
| 48565 |
51708 |
OAF1 |
Oleate-activated
transcription factor, acts alone and as a heterodimer with Pip2p;
activates genes involved in beta-oxidation of fatty acids and
peroxisome organization and biogenesis |
|
| 51856 |
52596 |
YAL049C |
Cytoplasmic
protein of unknown function, potential Hsp82p interactor |
|
| 52802 |
54790 |
GEM1 |
Evolutionarily-conserved
tail-anchored outer mitochondrial membrane GTPase which regulates
mitochondrial morphology; cells lacking Gem1p contain collapsed,
globular, or grape-like mitochondria; not required for
pheromone-induced cell death |
|
| 54990 |
56858 |
SPC72 |
Component
of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole
bodies and links them to microtubules; has roles in astral microtubule
formation and stabilization |
|
| 57030 |
57386 |
YAL046C |
Putative
protein of unknown function; YAL046C is not an essential gene |
|
| 57519 |
57851 |
YAL044W-A |
Putative
protein of unknown function; similar to S. pombe uvi31 which is a
putative DNA repair protein |
|
| 57951 |
58463 |
GCV3 |
H
subunit of the mitochondrial glycine decarboxylase complex, required
for the catabolism of glycine to 5,10-methylene-THF; expression is
regulated by levels of levels of 5,10-methylene-THF in the cytoplasm |
|
| 58696 |
61053 |
PTA1 |
Subunit
of holo-CPF, a multiprotein complex and functional homolog of mammalian
CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA
3' ends; involved in pre-tRNA processing; binds to the phosphorylated
CTD of RNAPII |
|
| 61317 |
62564 |
ERV46 |
Protein
localized to COPII-coated vesicles, forms a complex with Erv41p;
involved in the membrane fusion stage of transport |
|
| 62841 |
65405 |
CDC24 |
Guanine
nucleotide exchange factor (GEF or GDP-release factor) for Cdc42p;
required for polarity establishment and maintenance, and mutants have
morphological defects in bud formation and shmooing |
|
| 65779 |
67521 |
CLN3 |
G1
cyclin involved in cell cycle progression; activates Cdc28p kinase to
promote the G1 to S phase transition; plays a role in regulating
transcription of the other G1 cyclins, CLN1 and CLN2; regulated by
phosphorylation and proteolysis |
|
| 68717 |
69526 |
CYC3 |
Cytochrome
c heme lyase (holocytochrome c synthase), attaches heme to
apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane
space; human ortholog may have a role in microphthalmia with linear
skin defects (MLS) |
|
| 71787 |
73289 |
CDC19 |
Pyruvate
kinase, functions as a homotetramer in glycolysis to convert
phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or
anaerobic (glucose fermentation) respiration |
|
| 73427 |
73519 |
YAL037C-A |
Putative
protein of unknown function |
|
| 74021 |
74824 |
YAL037W |
Putative
protein of unknown function |
|
| 75044 |
76153 |
RBG1 |
Member of
the DRG family of GTP-binding proteins; interacts with translating
ribosomes and with Tma46p |
|
| 76428 |
79436 |
FUN12 |
GTPase,
required for general translation initiation by promoting Met-tRNAiMet
binding to ribosomes and ribosomal subunit joining; homolog of
bacterial IF2 |
|
| 79719 |
80588 |
MTW1 |
Essential
component of the MIND kinetochore complex (Mtw1p Including
Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to
those contacting microtubules; critical to kinetochore assembly |
|
| 80711 |
81952 |
FUN19 |
Non-essential
protein of unknown function |
|
| 82707 |
83228 |
POP5 |
Subunit
of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which
cleaves tRNA precursors to generate mature 5' ends |
|
| 83336 |
84475 |
PRP45 |
Protein
required for pre-mRNA splicing; associates with the spliceosome and
interacts with splicing factors Prp22p and Prp46p; orthologous to human
transcriptional coactivator SKIP and can activate transcription of a
reporter gene |
|
| 84750 |
87032 |
GIP4 |
Cytoplasmic
Glc7-interacting protein whose overexpression relocalizes Glc7p from
the nucleus and prevents chromosome segregation; potential Cdc28p
substrate |
|
| 87287 |
87753 |
SNC1 |
Vesicle
membrane receptor protein (v-SNARE) involved in the fusion between
Golgi-derived secretory vesicles with the plasma membrane; proposed to
be involved in endocytosis; member of the synaptobrevin/VAMP family of
R-type v-SNARE proteins |
|
| 87856 |
92271 |
MYO4 |
One
of two type V myosin motors (along with MYO2) involved in actin-based
transport of cargos; required for mRNA transport, including ASH1 mRNA,
and facilitating the growth and movement of ER tubules into the growing
bud along with She3p |
|
| 92901 |
94487 |
FRT2 |
Tail-anchored
endoplasmic reticulum membrane protein, interacts with homolog Frt1p
but is not a substrate of calcineurin (unlike Frt1p), promotes growth
in conditions of high Na+, alkaline pH, or cell wall stress; potential
Cdc28p substrate |
|
| 94688 |
95473 |
SAW1 |
Putative
protein of unknown function; green fluorescent protein (GFP)-fusion
protein localizes to the nucleus; YAL027W is a non-essential gene |
|
| 95631 |
99698 |
DRS2 |
Aminophospholipid
translocase (flippase) that maintains membrane lipid asymmetry in
post-Golgi secretory vessicles; contributes to clathrin-coated vesicle
formation and endocytosis; mutations in human homolog ATP8B1 result in
liver disease |
|
| 100226 |
101146 |
MAK16 |
Essential
nuclear protein, constituent of 66S pre-ribosomal particles; required
for maturation of 25S and 5.8S rRNAs; required for maintenance of M1
satellite double-stranded RNA of the L-A virus |
|
| 101566 |
105873 |
LTE1 |
Putative
GDP/GTP exchange factor required for mitotic exit at low temperatures;
acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is
a key regulator of mitotic exit; physically associates with Ras2p-GTP |
|
| 106273 |
108552 |
PMT2 |
Protein
O-mannosyltransferase, transfers mannose residues from dolichyl
phosphate-D-mannose to protein serine/threonine residues; acts in a
complex with Pmt1p, can instead interact with Pmt5p in some conditions;
target for new antifungals |
|
| 108878 |
110431 |
FUN26 |
Nucleoside
transporter with broad nucleoside selectivity; localized to
intracellular membranes |
|
| 110847 |
113360 |
CCR4 |
Component
of the CCR4-NOT transcriptional complex, which is involved in
regulation of gene expression; component of the major cytoplasmic
deadenylase, which is involved in mRNA poly(A) tail shortening |
|
| 113615 |
114616 |
ATS1 |
Protein
required, with Elongator complex, Kti11p, and Kti12p, for modification
of wobble nucleosides in tRNA; has a potential role in regulatory
interactions between microtubules and the cell cycle |
|
| 114920 |
118315 |
FUN30 |
Protein
whose overexpression affects chromosome stability, potential Cdc28p
substrate; homolog of Snf2p; the authentic, non-tagged protein is
detected in highly purified mitochondria in high-throughput studies |
|
| 118565 |
119542 |
YAL018C |
Putative
protein of unknown function |
|
| 120226 |
124296 |
PSK1 |
One
of two (see also PSK2) PAS domain containing S/T protein kinases;
coordinately regulates protein synthesis and carbohydrate metabolism
and storage in response to a unknown metabolite that reflects
nutritional status |
|
| 124880 |
126787 |
TPD3 |
Regulatory
subunit A of the heterotrimeric protein phosphatase 2A, which also
contains regulatory subunit Cdc55p and either catalytic subunit Pph21p
or Pph22p; required for cell morphogenesis and for transcription by RNA
polymerase III |
|
| 126904 |
128103 |
NTG1 |
DNA
N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base
excision repair, localizes to the nucleus and mitochondrion |
|
| 128253 |
129020 |
SYN8 |
Endosomal
SNARE related to mammalian syntaxin 8 |
|
| 129271 |
130533 |
DEP1 |
Transcriptional
modulator involved in regulation of structural phospholipid
biosynthesis genes and metabolically unrelated genes, as well as
maintenance of telomeres, mating efficiency, and sporulation |
|
| 130802 |
131986 |
CYS3 |
Cystathionine
gamma-lyase, catalyzes one of the two reactions involved in the
transsulfuration pathway that yields cysteine from homocysteine with
the intermediary formation of cystathionine |
|
| 132202 |
134079 |
SWC3 |
Protein
of unknown function, component of the SWR1 complex, which exchanges
histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required
for formation of nuclear-associated array of smooth endoplasmic
reticulum known as karmellae |
|
| 134186 |
135667 |
MDM10 |
Subunit
of both the Mdm10-Mdm12-Mmm1 complex and the mitochondrial sorting and
assembly machinery (SAM complex); functions in both the general and
Tom40p-specific pathways for import and assembly of outer membrane
beta-barrel proteins |
|
| 135856 |
136635 |
SPO7 |
Regulatory
subunit of Nem1p-Spo7p phosphatase holoenzyme, which regulates nuclear
growth by controlling recruitment of Pah1p onto promoters of
phospholipid biosynthetic genes; required for normal nuclear envelope
morphology and sporulation |
|
| 136916 |
137512 |
FUN14 |
Mitochondrial
protein of unknown function |
|
| 137700 |
138347 |
ERP2 |
Protein
that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p;
member, along with Emp24p and Erv25p, of the p24 family involved in ER
to Golgi transport and localized to COPII-coated vesicles |
|
| 139154 |
139256 |
TRN1 |
tRNA-Pro |
|
| 139505 |
141433 |
SSA1 |
ATPase
involved in protein folding and nuclear localization signal
(NLS)-directed nuclear transport; member of heat shock protein 70
(HSP70) family; forms a chaperone complex with Ydj1p; localized to the
nucleus, cytoplasm, and cell wall |
|
| 142176 |
143162 |
EFB1 |
Translation
elongation factor 1 beta; stimulates nucleotide exchange to regenerate
EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex,
which facilitates binding of aminoacyl-tRNA to the ribosomal A site |
|
| 143709 |
147533 |
VPS8 |
Membrane-associated
protein that interacts with Vps21p to facilitate soluble vacuolar
protein localization; component of the CORVET complex; required for
localization and trafficking of the CPY sorting receptor; contains RING
finger motif |
|
| 147596 |
151168 |
TFC3 |
Largest
of six subunits of the RNA polymerase III transcription initiation
factor complex (TFIIIC); part of the TauB domain of TFIIIC that binds
DNA at the BoxB promoter sites of tRNA and similar genes; cooperates
with Tfc6p in DNA binding |
|
| 152259 |
153878 |
NUP60 |
Subunit
of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC
in a process controlled by the nucleoplasmic concentration of
Gsp1p-GTP; potential Cdc28p substrate; involved in telomere maintenance |
|
| 154067 |
154726 |
ERP1 |
Protein
that forms a heterotrimeric complex with Erp2p, Emp24p, and Erv25p;
member, along with Emp24p and Erv25p, of the p24 family involved in ER
to Golgi transport and localized to COPII-coated vesicles |
|
| 155007 |
156287 |
SWD1 |
Subunit
of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4
and is required in transcriptional silencing near telomeres; WD40 beta
propeller superfamily member with similarity to mammalian Rbbp7 |
|
| 156756 |
158621 |
RFA1 |
Subunit
of heterotrimeric Replication Protein A (RPA), which is a highly
conserved single-stranded DNA binding protein involved in DNA
replication, repair, and recombination |
|
| 158967 |
159794 |
SEN34 |
Subunit
of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p,
Sen34p, and Sen54p; Sen34p contains the active site for tRNA 3' splice
site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing
endonuclease |
|
| 160598 |
164188 |
YAR009C |
Retrotransposon
TYA Gag and TYB Pol genes; in YARCTY1-1 TYB is mutant and probably
non-functional |
|
| 164545 |
165867 |
YAR010C |
Retrotransposon
TYA Gag gene co-transcribed with TYB Pol; in YARCTY1-1 TYB is mutant
and probably non-functional |
|
| 166268 |
166340 |
TA(UGC)A |
tRNA-Ala |
|
| 166743 |
168866 |
BUD14 |
Protein
involved in bud-site selection, Bud14p-Glc7p complex functions as a
cortical regulator of dynein; diploid mutants display a random budding
pattern instead of the wild-type bipolar pattern |
|
| 169370 |
170290 |
ADE1 |
N-succinyl-5-aminoimidazole-4-carboxamide
ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide
biosynthesis; red pigment accumulates in mutant cells deprived of
adenine |
|
| 170391 |
171698 |
KIN3 |
Nonessential
protein kinase with unknown cellular role |
|
| 172209 |
175133 |
CDC15 |
Protein
kinase of the Mitotic Exit Network that is localized to the spindle
pole bodies at late anaphase; promotes mitotic exit by directly
switching on the kinase activity of Dbf2p |
|
| 176854 |
177021 |
PAU7 |
Part
of 23-member seripauperin multigene family, active during alcoholic
fermentation, regulated by anaerobiosis, inhibited by oxygen, repressed
by heme |
|
| 179279 |
179818 |
YAR023C |
Putative
integral membrane protein, member of DUP240 gene family |
|
| 181135 |
181248 |
SUP56 |
tRNA-Leu |
|
| 182516 |
182597 |
TS(AGA)A |
tRNA-Ser |
|
| 183764 |
184471 |
UIP3 |
Putative
integral membrane protein of unknown function; interacts with Ulp1p at
the nuclear periphery; member of DUP240 gene family |
|
| 184886 |
185590 |
YAR028W |
Putative
integral membrane protein, member of DUP240 gene family; GFP-fusion
protein is induced in response to the DNA-damaging agent MMS |
|
| 186315 |
186539 |
YAR029W |
Member
of DUP240 gene family but contains no transmembrane domains; green
fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in
a punctate pattern |
|
| 186830 |
187726 |
PRM9 |
Pheromone-regulated
protein with 3 predicted transmembrane segments and an FF sequence, a
motif involved in COPII binding; member of DUP240 gene family |
|
| 188101 |
188805 |
MST28 |
Putative
integral membrane protein, involved in vesicle formation; forms complex
with Mst27p; member of DUP240 gene family; binds COPI and COPII vesicles |
|
| 190187 |
192250 |
YAT1 |
Outer
mitochondrial carnitine acetyltransferase, minor ethanol-inducible
enzyme involved in transport of activated acyl groups from the
cytoplasm into the mitochondrial matrix; phosphorylated |
|
| 192331 |
192411 |
YAR035C-A |
Putative
protein of unknown function; identified by gene-trapping,
microarray-based expression analysis, and genome-wide homology searching |
|
| 192613 |
196179 |
SWH1 |
Protein
similar to mammalian oxysterol-binding protein; contains ankyrin
repeats; localizes to the Golgi and the nucleus-vacuole junction |
|
| 203394 |
208007 |
FLO1 |
Lectin-like
protein involved in flocculation, cell wall protein that binds to
mannose chains on the surface of other cells, confers floc-forming
ability that is chymotrypsin sensitive and heat resistant; similar to
Flo5p |
|
| 218131 |
218334 |
YAR061W |
|
|
| 218540 |
219136 |
YAR062W |
|
|
| 220189 |
220488 |
YAR064W |
Putative
protein of unknown function |
|
| 221040 |
221651 |
YAR066W |
Putative GPI
protein |
|
| 222397 |
222882 |
YAR068W |
Fungal-specific
protein of unknown function; induced in respiratory-deficient cells |
|
| 225451 |
226854 |
PHO11 |
One
of three repressible acid phosphatases, a glycoprotein that is
transported to the cell surface by the secretory pathway; induced by
phosphate starvation and coordinately regulated by PHO4 and PHO2 |
|